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42 C.F.R. § 81.25

Guidelines for claims including two or more primary cancers.

§ 81.25 Guidelines for claims including two or more primary cancers.

For claims including two or more primary cancers, DOL will use NIOSH-IREP to calculate the estimated probability of causation for each cancer individually. Then DOL will perform the following calculation using the probability of causation estimates produced by NIOSH-IREP:

Equation 1

Calculate: 1−[{1−PC1} × {1−PC2} × . . . × {1−PCn}] = PCtotal,
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